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Design of Oligonucleotides for Allele-Specific Amplification Based on PCR and Isothermal Techniques.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Tortajada-Genaro Luis Antonio

Abstract excerpt

Single-nucleotide variations have been associated to various genetic diseases, variations on drug efficiency, and differences in cancer prognostics. The detection of these changes in nucleic acid sequences from patient samples is particularly useful for accurate diagnosis, therapeutics, and disease management. A reliable allele-specific amplification is still an important challenge for molecular-based diagnostic...

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PMID: 34773613
DOI: 10.1007/978-1-0716-1799-1_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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