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Article

Evidence of a Cardiovascular Function for Microtubule-Associated Protein Tau.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Betrie Ashenafi H, Ayton Scott, Bush Ashley I, Angus James A, Lei Peng, Wright Christine E

Abstract excerpt

Aggregation of tau protein into intracellular deposits is a pathognomonic feature of tauopathies such as Alzheimer's disease (AD) and lowering tau is a prominent therapeutic strategy under development. However, the physiological function of tau protein is not well known, particularly in the periphery. Lowering tau protein risks disrupting its physiological role leading to unwanted effects. In this study, the...

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Identifiers

PMID: 28059795
DOI: 10.3233/JAD-161093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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