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Article

Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division.

Scientific reports - 6 Jan 2017

Abadía-Molina Francisco, Morón-Calvente Virginia, Baird Stephen D, Shamim Fahad, Martín Francisco, MacKenzie Alex

Abstract excerpt

The neuronal apoptosis inhibitory protein (NAIP) is a constituent of the inflammasome and a key component of the innate immune system. Here we use immunofluorescence to position NAIP within the cytokinetic apparatus, contiguous to chromosomal passenger complex (CPC), Centralspindlin, PRC1 and KIF4A. During metaphase, NAIP accumulates in the mitotic spindle poles and is shown in spindle microtubules; in anaphase...

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Source

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Identifiers

PMID: 28059125
DOI: 10.1038/srep39981
PMCID: PMC5216396

Genes

NAIP
PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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