Article
The Nek6 and Nek7 protein kinases are required for robust mitotic spindle formation and cytokinesis.
Molecular and cellular biology - 1 Jul 2009
O'Regan Laura, Fry Andrew M
Abstract excerpt
Nek6 and Nek7 are members of the NIMA-related serine/threonine kinase family. Previous work showed that they contribute to mitotic progression downstream of another NIMA-related kinase, Nek9, although the roles of these different kinases remain to be defined. Here, we carried out a comprehensive analysis of the regulation and function of Nek6 and Nek7 in human cells. By generating specific antibodies, we show...
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