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Article

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.

The Journal of biological chemistry - 24 Mar 2017

Matthews Sarah, Belcher James D, Tee Kang Lan, Girvan Hazel M, McLean Kirsty J, Rigby Stephen E J, Levy Colin W, Leys David, Parker David A, Blankley Richard T, Munro Andrew W

Abstract excerpt

The Jeotgalicoccus sp. peroxygenase cytochrome P450 OleTJE (CYP152L1) is a hydrogen peroxide-driven oxidase that catalyzes oxidative decarboxylation of fatty acids, producing terminal alkenes with applications as fine chemicals and biofuels. Understanding mechanisms that favor decarboxylation over fatty acid hydroxylation in OleTJE could enable protein engineering to improve catalysis or to introduce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28053093
DOI: 10.1074/jbc.M116.762336
PMCID: PMC5377825

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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