Article
CRISPR/Cas9-mediated genome editing: From basic research to translational medicine.
Journal of cellular and molecular medicine - 1 Apr 2020
Jacinto Filipe V, Link Wolfgang, Ferreira Bibiana I
Abstract excerpt
The recent development of the CRISPR/Cas9 system as an efficient and accessible programmable genome-editing tool has revolutionized basic science research. CRISPR/Cas9 system-based technologies have armed researchers with new powerful tools to unveil the impact of genetics on disease development by enabling the creation of precise cellular and animal models of human diseases. The therapeutic potential of these...
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