Article
Current approaches in CRISPR-Cas9 mediated gene editing for biomedical and therapeutic applications.
Journal of controlled release : official journal of the Controlled Release Society - 1 Mar 2022
Bhattacharjee Gargi, Gohil Nisarg, Khambhati Khushal, Mani Indra, Maurya Rupesh, Karapurkar Janardhan Keshav, Gohil Jigresh, Chu Dinh-Toi, Vu-Thi Hue, Alzahrani Khalid J, Show Pau-Loke, Rawal Rakesh M, Ramakrishna Suresh, Singh Vijai
Abstract excerpt
A single gene mutation can cause a number of human diseases that affect the quality of life. Until the development of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) systems, it was challenging to correct a gene mutation to avoid a disease by reverting phenotypes. The advent of CRISPR technology has changed the field of gene editing, given its simplicity and...
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