Article
Heterogeneous Spatial Distribution of Transcriptional Activity in Budding Yeast Nuclei.
Biophysical journal - 7 Feb 2017
Tokuda Naoko, Sasai Masaki
Abstract excerpt
Recent microscopic and simulation studies have shown that the genome structure fluctuates dynamically in the nuclei of budding yeast Saccharomyces cerevisiae. This genome-wide movement should lead to the fluctuations of individual genes in their territorial regions. This raises an intriguing question of whether the resulting distribution of genes is correlated to their transcriptional activity. An effective...
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