Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Noise reduction facilitated by dosage compensation in gene networks.

Nature communications - 3 Oct 2016

Peng Weilin, Song Ruijie, Acar Murat

Abstract excerpt

Genetic noise together with genome duplication and volume changes during cell cycle are significant contributors to cell-to-cell heterogeneity. How can cells buffer the effects of these unavoidable epigenetic and genetic variations on phenotypes that are sensitive to such variations? Here we show that a simple network motif that is essential for network-dosage compensation can reduce the effects of extrinsic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dosage Compensation, Genetic
Share to Amino Acid Motifs
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Gene Regulatory Networks

Share to Genes, Synthetic

Share to Haploidy

Share to Stochastic Processes

Source

Open in PubMed Open full text

Identifiers

PMID: 27694830
DOI: 10.1038/ncomms12959
PMCID: PMC5063963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Noise reduction facilitated by dosage compensation in gene networks.PMID 27694830Read ↗

Interplay between copy number, dosage compensation and expression noise in <i>Drosophila</i>Semantic proximity Read ↗

Noise in biological systems: pros, cons, and mechanisms of control.Semantic proximity Read ↗

Being noisy in a crowd: Differential selective pressure on gene expression noise in model gene regulatory networks.Semantic proximity Read ↗

Feed-forward loop circuits as a side effect of genome evolution.Semantic proximity Read ↗

Allele-specific single-cell RNA sequencing reveals different architectures of intrinsic and extrinsic gene expression noises.Semantic proximity Read ↗

Single-cell RNA-seq reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stressSemantic proximity Read ↗

From fluctuations to phenotypes: the physiology of noise.Semantic proximity Read ↗

Complex topology rather than complex membership is a determinant of protein dosage sensitivity.Semantic proximity Read ↗

Global propagation of genetic perturbation effects through genome-wide stoichiometry conservation architectureSemantic proximity Read ↗

Relevance of phenotypic noise to adaptation and evolution.Semantic proximity Read ↗

Adjusting phenotypes by noise control.Semantic proximity Read ↗

Adaptive noise.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.