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Article

Single nucleotide polymorphisms associated with colorectal cancer susceptibility and loss of heterozygosity in a Taiwanese population.

PloS one - 1 Jan 2014

Yang Chih-Yung, Lu Ruey-Hwa, Lin Chien-Hsing, Jen Chih-Hung, Tung Chien-Yi, Yang Shung-Haur, Lin Jen-Kou, Jiang Jeng-Kai, Lin Chi-Hung

Abstract excerpt

Given the significant racial and ethnic diversity in genetic variation, we are intrigued to find out whether the single nucleotide polymorphisms (SNPs) identified in genome-wide association studies of colorectal cancer (CRC) susceptibility in East Asian populations are also relevant to the population of Taiwan. Moreover, loss of heterozygosity (LOH) may provide insight into how variants alter CRC risk and how...

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Source

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Identifiers

PMID: 24968322
DOI: 10.1371/journal.pone.0100060
PMCID: PMC4072675

Genes

BMP4
CCND2

Provenance

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