Article
DJ-1 promotes development of DEN-induced hepatocellular carcinoma and proliferation of liver cancer cells.
Oncotarget - 31 Jan 2017
Qiu Bijun, Wang Junqi, Yu Yingxue, Zhen Chao, Gu Jinyang, Liu Wenjun, Wen Yankai, Chen Lili, Gao Yueqiu, Xia Qiang, Kong Xiaoni
Abstract excerpt
Chronic liver inflammation and injuries play a critical role in development of hepatocellular carcinoma (HCC). Parkinson disease (autosomal recessive, early onset) 7, encoding PARK7 protein (also called DJ-1), plays important roles in many carcinogenesis processes and is essential in modulating inflammation. However, whether DJ-1 is involved in HCC development remains largely unknown. To determine the effect of...
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