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The Tale of DJ-1 (PARK7): A Swiss Army Knife in Biomedical and Psychological Research

18 Apr 2023

Abstract excerpt

DJ-1 (also known as PARK7) is a multifunctional enzyme in human beings that is highly conserved and that has also been discovered in diverse species (ranging from prokaryotes to eukaryotes). Its complex enzymatic and non-enzymatic activities (such as anti-oxidation, anti-glycation, and protein quality control), as well as its role as a transcriptional coactivator, enable DJ-1 to serve as an essential regulator in...

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PMID: 37108572
DOI: 10.3390/ijms24087409

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