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Article

Collective Resistance in Microbial Communities by Intracellular Antibiotic Deactivation

27 Dec 2016

Abstract excerpt

The structure and composition of bacterial communities can compromise antibiotic efficacy. For example, the secretion of β-lactamase by individual bacteria provides passive resistance for all residents within a polymicrobial environment. Here, we uncover that collective resistance can also develop via intracellular antibiotic deactivation. Real-time luminescence measurements and single-cell analysis demonstrate...

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Share to Antibiotic Resistance in Bacteria
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28027306
DOI: 10.1371/journal.pbio.2000631

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