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Article

Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis.

Biochimica et biophysica acta. Biomembranes - 1 Sept 2017

Holowka David, Baird Barbara

Abstract excerpt

The cell surface receptor for epidermal growth factor (EGFR), a receptor tyrosine kinase, is a key player in normal cell growth and proliferation. Mutations in this receptor often lead to oncological transformation and other pathologies. Because of its representation of the receptor tyrosine kinase family and its important role in health and disease, a broad range of studies have been carried out in many...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28024796
DOI: 10.1016/j.bbamem.2016.12.015
PMCID: PMC5483208

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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