Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cells

25 Dec 2016

Abstract excerpt

Stable breast cancer cell (BCC) lines are valuable tools for the identification of breast cancer stem cell (BCSC) phenotypes that develop in response to several stimuli as well as for studying the basic mechanisms associated with the initiation and maintenance of BCSCs. However, the characteristics of individual, BCC‐derived BCSCs varies and these cells show distinct phenotypes depending on the different BCSC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28012234
DOI: 10.1111/cas.13147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxia promotes the phenotypic change of aldehyde dehydrogenase activity of breast cancer stem cellsPMID 28012234Read ↗

ALDHHigh Breast Cancer Stem Cells Exhibit a Mesenchymal-Senescent Hybrid Phenotype, with Elevated Metabolic and Migratory Activities.Semantic proximity Read ↗

Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics.Semantic proximity Read ↗

Heterogeneity of normal human breast stem and progenitor cells as revealed by transcriptional profilingSemantic proximity Read ↗

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.Semantic proximity Read ↗

Regulation of the breast cancer stem cell phenotype by hypoxia-inducible factors.Semantic proximity Read ↗

Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling.Semantic proximity Read ↗

Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancerSemantic proximity Read ↗

The Concept of Cancer Stem Cells: Elaborating on ALDH1B1 as an Emerging Marker of Cancer ProgressionSemantic proximity Read ↗

High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas.Semantic proximity Read ↗

Novel molecular regulators of breast cancer stem cell plasticity and heterogeneitySemantic proximity Read ↗

Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of MetastasisSemantic proximity Read ↗

Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.