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Article

Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation.

Biochemical and biophysical research communications - 29 Jan 2017

Park Kyoung Ryoung, An Jun Yop, Kang Jung Youn, Lee Jung-Gyu, Lee Youngjin, Mun Sang A, Jun Chang-Duk, Song Woo Keun, Eom Soo Hyun

Abstract excerpt

EF-hand domain-containing protein D2/Swiprosin-1 (EFhd2) is an actin-binding protein mainly expressed in the central nervous and the immune systems of mammals. Intracellular events linked to EFhd2, such as membrane protrusion formation, cell adhesion, and BCR signaling, are triggered by the association of EFhd2 and F-actin. We previously reported that Ca2+ enhances the F-actin-bundling ability of EFhd2 through...

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Source

Identifiers

PMID: 28011271
DOI: 10.1016/j.bbrc.2016.12.124

Genes

BCR
EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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