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Article

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.

Structure (London, England : 1993) - 1 Aug 2017

Ecsédi Péter, Kiss Bence, Gógl Gergő, Radnai László, Buday László, Koprivanacz Kitti, Liliom Károly, Leveles Ibolya, Vértessy Beáta, Jeszenői Norbert, Hetényi Csaba, Schlosser Gitta, Katona Gergely, Nyitray László

Abstract excerpt

Annexin A2 (ANXA2) has a versatile role in membrane-associated functions including membrane aggregation, endo- and exocytosis, and it is regulated by post-translational modifications and protein-protein interactions through the unstructured N-terminal domain (NTD). Our sequence analysis revealed a short motif responsible for clamping the NTD to the C-terminal core domain (CTD). Structural studies indicated that...

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Identifiers

PMID: 28669632
DOI: 10.1016/j.str.2017.06.001

Genes

ANXA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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