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1,2-Diacylglycerol choline phosphotransferase catalyzes the final step in the unique Treponema denticola phosphatidylcholine biosynthesis pathway.

Molecular microbiology - 1 Mar 2017

Vences-Guzmán Miguel Ángel, Paula Goetting-Minesky M, Guan Ziqiang, Castillo-Ramirez Santiago, Córdoba-Castro Luz América, López-Lara Isabel M, Geiger Otto, Sohlenkamp Christian, Christopher Fenno J

Abstract excerpt

Treponema denticola synthesizes phosphatidylcholine through a licCA-dependent CDP-choline pathway identified only in the genus Treponema. However, the mechanism of conversion of CDP-choline to phosphatidylcholine remained unclear. We report here characterization of TDE0021 (herein designated cpt) encoding a 1,2-diacylglycerol choline phosphotransferase homologous to choline phosphotransferases that catalyze the...

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PMID: 28009086
DOI: 10.1111/mmi.13596
PMCID: PMC5682592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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