Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Treponema denticola PrcB Is Required for Expression and Activity of the PrcA-PrtP (Dentilisin) Complex

1 May 2010

Abstract excerpt

The Treponema denticola surface protease complex, consisting of PrtP protease (dentilisin) and two auxiliary polypeptides (PrcA1 and PrcA2), is believed to contribute to periodontal disease by degrading extracellular matrix components and disrupting host intercellular signaling. Previously, we showed that transcription of the protease operon initiates upstream of TDE0760 (herein designated prcB), the open reading...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Peptides and Activities
Share to Bone and Dental Protein Studies
Share to Oral microbiology and periodontitis research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20435733
DOI: 10.1128/jb.00274-10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Treponema denticola PrcB Is Required for Expression and Activity of the PrcA-PrtP (Dentilisin) ComplexPMID 20435733Read ↗

Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression in Treponema denticolaSemantic proximity Read ↗

Conservation and revised annotation of the Treponema denticola prcB-prcA-prtP locus encoding the dentilisin (CTLP) protease complex.Semantic proximity Read ↗

Mutagenesis of a novel gene in the prcA-prtP protease locus affects expression of Treponema denticola membrane complexes.Semantic proximity Read ↗

Localization and pathogenic role of the cysteine protease dentipain in Treponema denticolaSemantic proximity Read ↗

Characterization of the Treponema denticola Virulence Factor Dentilisin.Semantic proximity Read ↗

<i>Treponema denticola</i> dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cellsSemantic proximity Read ↗

Dentilisin Activity Affects the Organization of the Outer Sheath of<i>Treponema denticola</i>Semantic proximity Read ↗

Characterization of a novel potential peptide import system in Treponema denticola.Semantic proximity Read ↗

The opdB locus encodes the trypsin-like peptidase activity of Treponema denticola.Semantic proximity Read ↗

Identification of a Treponema denticola OppA homologue that binds host proteins present in the subgingival environment.Semantic proximity Read ↗

Treponema denticola major surface protein (Msp): a key player in periodontal pathogenicity and immune evasionSemantic proximity Read ↗

Characterization of a novel family of fibronectin‐binding proteins with M23 peptidase domains from Treponema denticolaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.