Article
Integrin-Targeting Fluorescent Proteins: Exploration of RGD Insertion Sites.
Chembiochem : a European journal of chemical biology - 2 Mar 2017
Sonntag Michael H, Schill Jurgen, Brunsveld Luc
Abstract excerpt
The potential of the fluorescent protein scaffold to control peptide sequence functionality is illustrated by an exploration of fluorescent proteins as novel probes for targeting integrins. A library of fluorescent mCitrine proteins with RGD motifs incorporated at several positions in loops within the protein main chain was generated and characterized. Amino acid mutations to RGD as well as RGD insertions were...
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