Structural and functional aspects of RGD-containing protein antagonists of glycoprotein IIb-IIIa.

doi:10.1016/0958-1669(93)90009-l

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Article

Structural and functional aspects of RGD-containing protein antagonists of glycoprotein IIb-IIIa.

Current opinion in biotechnology - 1 Aug 1993

Lazarus R A, McDowell R S

Abstract excerpt

In the past few years, knowledge of the structure and function of RGD-containing protein antagonists of the platelet fibrinogen receptor glycoprotein IIb-IIIa has advanced rapidly. The RGD sequence is found at the apex of extended, solvent accessible, and conformationally flexible loops in protei...

Topics

Amino Acid Sequence
Animals
Biotechnology
Models, Molecular
Molecular Sequence Data
Mutation
Oligopeptides
Platelet Membrane Glycoproteins
Proteins

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