Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inclusion of an RGD Motif Alters Invasin Integrin-Binding Affinity and Specificity.

Biochemistry - 12 Apr 2016

Khan Tarik A, Wang Xianzhe, Maynard Jennifer A

Abstract excerpt

Invasin is a key adhesin displayed on the outer membrane of Yersinia enterocolitica and Y. pseudotuberculosis that mediates the initial stages of infection. Invasin specifically targets microfold (M) cells in the small intestine by binding β1 integrins and is sufficient to trigger eukaryotic uptake of invasin-coated particles, including Yersinia, Escherichia coli, and latex beads. As a result, invasin has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adhesins, Bacterial
Share to Caco-2 Cells
Share to Cricetulus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enterocytes

Share to Gene Library

Share to Oligopeptides

Share to Protein Interaction Domains and Motifs

Share to Yersinia enterocolitica

Source

Identifiers

PMID: 27015583
DOI: 10.1021/acs.biochem.5b01243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inclusion of an RGD Motif Alters Invasin Integrin-Binding Affinity and Specificity.PMID 27015583Read ↗

A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association.Semantic proximity Read ↗

Role of the beta1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia.Semantic proximity Read ↗

SWIM analysis allows rapid identification of residues involved in invasin-mediated bacterial uptake.Semantic proximity Read ↗

The identification of exported proteins with gene fusions to invasin.Semantic proximity Read ↗

Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium.Semantic proximity Read ↗

Defining the Ail Ligand-Binding Surface: Hydrophobic Residues in Two Extracellular Loops Mediate Cell and Extracellular Matrix Binding To Facilitate Yop Delivery.Semantic proximity Read ↗

Cellular internalization in the absence of invasin expression is promoted by the Yersinia pseudotuberculosis yadA product.Semantic proximity Read ↗

A genome-wide screen in macrophages defines host genes regulating the uptake of <i>Mycobacterium abscessus</i>Semantic proximity Read ↗

Rational Design of a Robust G-Quadruplex Aptamer as an Inhibitor to Alleviate Listeria monocytogenes Infection.Semantic proximity Read ↗

Expression and distribution of beta1 integrins in in vitro-induced M cells: implications for Yersinia adhesion to Peyer's patch epithelium.Semantic proximity Read ↗

Investigating the potential role of intimin/invasin in Aeromonas hydrophila virulence in Labeo rohita: a host-microbe interaction studySemantic proximity Read ↗

Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.