Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of ADH1B Arg47His, ALDH2 Glu487Lys, and CYP4502E1 polymorphisms in gastric cancer risk and interaction with environmental factors.

Genetics and molecular research : GMR - 19 Dec 2016

Chen Z H, Xian J F, Luo L P

Abstract excerpt

Gastric cancer is the fourth commonly diagnosed cancer and the second most frequent cause of cancer death worldwide. Genetic variations in ADH1B and ALDH2 may alter the function and activity of the corresponding enzymes, leading to differences in acetaldehyde exposure between drinkers. Cytochrome P4502E1 (CYP4502E1) is a phase I enzyme that plays an important role in metabolizing nitrosamine compounds and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alcohol Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Cytochrome P-450 CYP2E1

Share to Logistic Models

Share to Polymorphism, Genetic

Share to Stomach Neoplasms

Source

Identifiers

PMID: 28002588
DOI: 10.4238/gmr15048904

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of ADH1B Arg47His, ALDH2 Glu487Lys, and CYP4502E1 polymorphisms in gastric cancer risk and interaction with environmental factors.PMID 28002588Read ↗

Effects of alcohol consumption, ALDH2 rs671 polymorphism, and Helicobacter pylori infection on the gastric cancer risk in a Korean population.Semantic proximity Read ↗

Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China.Semantic proximity Read ↗

Genetic polymorphisms of ADH1B, ADH1C and ALDH2, alcohol consumption, and the risk of gastric cancer: the Japan Public Health Center-based prospective study.Semantic proximity Read ↗

Polymorphisms in ADH1B and ALDH2 genes associated with the increased risk of gastric cancer in West Bengal, India.Semantic proximity Read ↗

Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions.Semantic proximity Read ↗

ALDH2 and ADH1 genetic polymorphisms may contribute to the risk of gastric cancer: a meta-analysis.Semantic proximity Read ↗

Association between alcohol intake and risk for gastric cancer with regard to ALDH2 genotype in the Korean population.Semantic proximity Read ↗

Effect of ALDH2 polymorphism on cancer risk in AsiansSemantic proximity Read ↗

Impacts of ADH1B rs1229984 and ALDH2 rs671 polymorphisms on risks of alcohol-related disorder and cancer.Semantic proximity Read ↗

Aldehyde dehydrogenase 2 gene rs671 G>A polymorphism is associated with an increased risk of digestive tract cancer.Semantic proximity Read ↗

Case-control study on CYP4B1 gene polymorphism and susceptibility to gastric cancer in the chinese Han population.Semantic proximity Read ↗

Esophageal squamous cell carcinoma and ALDH2 and ADH1B polymorphisms in Chinese females.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.