Article
Esophageal squamous cell carcinoma and ALDH2 and ADH1B polymorphisms in Chinese females.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Wang Yulin, Ji Runli, Wei Xu, Gu Lili, Chen Linyan, Rong Yamei, Wang Ruitao, Zhang Zhengyun, Liu Baiqing, Xia Shihai
Abstract excerpt
AIM: Alcohol dehydrogenase-IB (ADH1B) and aldehyde dehydrogenase-2 (ALDH2) are the key enzymes for elimination of ethanol and acetaldehyde, the latter being an established animal carcinogen produced after drinking. In this study, we aimed to evaluate the contribution of ADH1B and ALDH2 polymorphisms to the risk of esophageal squamous cell (ESCC) in Chinese females. METHODS: A total of 81 pathologically-proven...
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