Article
TLR5 Polymorphisms rs2072493, rs5744174, and rs5744168 Are Not Genetic Risk Factors for Chronic Helicobacter pylori Infection in Indian Tamils.
Immunological investigations - 1 Aug 2017
Goda Vaishnavi, Jayaraman Megala, Loganathan Rekha, Nazeer Mehnaz, Ali Mohammed, Karunakaran Premkumar, Devaraju Panneer
Abstract excerpt
The incidence of Helicobacter pylori (H. pylori) infection and gastric cancer is on the rise in India, and the genetic factors influencing the increased susceptibility in Indian population remain obscure. Toll-like receptors (TLRs) play a major role in innate immune system and genetic polymorphisms affecting their function were reported to enhance the risk for H. pylori infection. Seventy-seven patients (n = 77)...
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