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A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA

7 Nov 2018

Abstract excerpt

Background: Breast cancer (BrC) is the most frequent neoplasm in women. New biomarkers, including aberrant DNA methylation, may improve BrC management. Herein, we evaluated the detection and prognostic performance of seven genes’ promoter methylation (APC, BRCA1, CCND2, FOXA1, PSAT1, RASSF1A and SCGB3A1). Methods: Methylation levels were assessed in primary BrC tissues by quantitative methylation-specific...

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PMID: 30405052
DOI: 10.3390/jcm7110420

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