Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms.

Pharmacogenomics - 1 Jan 2017

Ovenden Ellen S, Drögemöller Britt I, van der Merwe Lize, Chiliza Bonginkosi, Asmal Laila, Emsley Robin A, Warnich Louise

Abstract excerpt

AIM: Noncoding variation has demonstrated regulatory effects on disease treatment outcomes. This study investigated the potential functionality of previously implicated noncoding variants on schizophrenia treatment response. MATERIALS & METHODS: Predicted regulatory potential of variation identified from antipsychotic response genome-wide association studies was determined. Prioritized variants were assessed for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Genome-Wide Association Study

Share to Schizophrenia

Share to South Africa

Share to Treatment Outcome

Share to Young Adult

Source

Identifiers

PMID: 27992301
DOI: 10.2217/pgs-2016-0108

Genes

MANBA
NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms.PMID 27992301Read ↗

The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients.Semantic proximity Read ↗

Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort.Semantic proximity Read ↗

Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study.Semantic proximity Read ↗

Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients.Semantic proximity Read ↗

Identification of Schizophrenia-Risk Regulatory Variant rs1399178 in the Non-coding Region With Its Impact on NRF1 Binding.Semantic proximity Read ↗

Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response.Semantic proximity Read ↗

Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia.Semantic proximity Read ↗

Different responses to risperidone treatment in Schizophrenia: a multicenter genome-wide association and whole exome sequencing joint studySemantic proximity Read ↗

Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia.Semantic proximity Read ↗

Candidate-gene association analysis of response to risperidone in African-American and white patients with schizophrenia.Semantic proximity Read ↗

Analysis of gene variants previously associated with iloperidone response in patients with schizophrenia who are treated with risperidone.Semantic proximity Read ↗

Model-based gene selection shows engrailed 1 is associated with antipsychotic response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.