Article
Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients.
Pharmacogenomics - 1 Feb 2014
Drogemöller Britt I, Niehaus Dana J H, Chiliza Bonginkosi, van der Merwe Lize, Asmal Laila, Malhotra Anil K, Wright Galen E B, Emsley Robin, Warnich Louise
Abstract excerpt
AIM: Many antipsychotic pharmacogenetics studies have been performed examining candidate genes or known variation; however, our understanding of the genetic factors involved in antipsychotic pharmacogenetic traits remains limited. MATERIALS & METHODS: A well-characterized cohort of first-episode schizophrenia (FES) patients was used to identify a subset of nonresponders and responders to antipsychotic treatment...
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