Article
Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study.
The lancet. Psychiatry - 1 Apr 2018
Yu Hao, Yan Hao, Wang Lifang, Li Jun, Tan Liwen, Deng Wei, Chen Qi, Yang Guigang, Zhang Fuquan, Lu Tianlan, Yang Jianli, Li Keqing, Lv Luxian, Tan Qingrong, Zhang Hongyan, Xiao Xiao, Li Ming, Ma Xin, Yang Fude, Li Lingjiang, Wang Chuanyue, Li Tao, Zhang Dai, Yue Weihua
Abstract excerpt
BACKGROUND: Antipsychotic drugs improve schizophrenia symptoms and reduce the frequency of relapse, but treatment response is highly variable. Little is known about the genetic factors associated with treatment response. We did a genome-wide association study of antipsychotic treatment response in patients with schizophrenia. METHODS: The discovery cohort comprised patients with schizophrenia from 32 psychiatric...
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