Article
Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment.
Pharmacogenetics and genomics - 1 Feb 2013
Clark Shaunna L, Souza Renan P, Adkins Daniel E, Aberg Karolina, Bukszár József, McClay Joseph L, Sullivan Patrick F, van den Oord Edwin J C G
Abstract excerpt
OBJECTIVE: To examine the unique and congruent findings between multiple raters in a genome-wide association study (GWAS) in the context of understanding individual differences in treatment response during antipsychotic therapy for schizophrenia. MATERIALS AND METHODS: We performed GWAS to search for genetic variation affecting treatment response. The analysis sample included 738 patients with schizophrenia,...
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