Article
Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2014
Jenkins Aaron, Apud José A, Zhang Fengyu, Decot Heather, Weinberger Daniel R, Law Amanda J
Abstract excerpt
Neurexins are presynaptic neuronal adhesion molecules that interact with postsynaptic neuroligins to form an inter-synaptic complex required for synaptic specification and efficient neurotransmission. Deletions and point mutations in the neurexin 1 (NRXN1) gene are associated with a broad spectrum of neuropsychiatric and neurodevelopmental disorders, including autism, intellectual disability, epilepsy,...
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