Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes

19 Dec 2016

Abstract excerpt

An egg must be fertilized by a single sperm only. To prevent polyspermy, the zona pellucida, a structure that surrounds mammalian eggs, becomes impermeable upon fertilization, preventing the entry of further sperm. The structural changes in the zona upon fertilization are driven by the exocytosis of cortical granules. These translocate from the oocyte's centre to the plasma membrane during meiosis. However, very...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microtubule and mitosis dynamics
Share to Plant Reproductive Biology
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27991490
DOI: 10.1038/ncomms13726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytesPMID 27991490Read ↗

Knockin’ on Egg’s Door: Maternal Control of Egg Activation That Influences Cortical Granule Exocytosis in Animal SpeciesSemantic proximity Read ↗

Control of Membrane Fusion During Spermiogenesis and the Acrosome Reaction1Semantic proximity Read ↗

Regulating the acrosome reactionSemantic proximity Read ↗

The cortical reaction and development of activation competence in mammalian oocytesSemantic proximity Read ↗

Intrafollicular barriers and cellular interactions during ovarian follicle developmentSemantic proximity Read ↗

Transzonal projections: Essential structures mediating intercellular communication in the mammalian ovarian follicleSemantic proximity Read ↗

Unresolved Questions Concerning Mammalian Sperm Acrosomal Exocytosis1Semantic proximity Read ↗

Penetration, Adhesion, and Fusion in Mammalian Sperm-Egg InteractionSemantic proximity Read ↗

Cellular and molecular aspects of oocyte maturation and fertilization: a perspective from the actin cytoskeletonSemantic proximity Read ↗

Aberrant cortex contractions impact mammalian oocyte qualitySemantic proximity Read ↗

Molecular triggers of egg activation at fertilization in mammalsSemantic proximity Read ↗

The cell biology of fertilization: Gamete attachment and fusionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.