The cortical reaction and development of activation competence in mammalian oocytes

Abstract excerpt

Blocks to polyspermic fertilization are necessary to prevent the incorporation of two sperm nuclei into a zygote's genome, which would result in abnormal development. Many mammalian eggs utilize both an extracellular zona pellucida block to polyspermy and a plasma membrane block. Although little is known about the plasma membrane block in mammals, fertilization results in zona glycoprotein modifications caused by...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ovarian function and disorders
• Share to Reproductive Biology and Fertility
• Share to Sperm and Testicular Function