Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulating the acrosome reaction

1 Jan 2008

Abstract excerpt

The acrosome reaction is a secretory event that must be completed by the sperm of many animal species prior to fusion with eggs. In mammals, exocytosis in triggered by ZP3, a glycoprotein component of the egg pellucida, following gamete contact. ZP3 promotes a sustained influx of Ca2+ into sperm that is necessary for the acrosome reaction. Here, we discuss the mechanism by which ZP3 generates Ca2+ entry, as well...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Plant Reproductive Biology
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18649263
DOI: 10.1387/ijdb.082696hf

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulating the acrosome reactionPMID 18649263Read ↗

Ca<sup>2+</sup>Entry through Store-operated Channels in Mouse Sperm Is Initiated by Egg ZP3 and Drives the Acrosome ReactionSemantic proximity Read ↗

ZP3-dependent activation of sperm cation channels regulates acrosomal secretion during mammalian fertilization.Semantic proximity Read ↗

Control of Membrane Fusion During Spermiogenesis and the Acrosome Reaction1Semantic proximity Read ↗

A Perspective on the Control of Mammalian Fertilization by Egg-Activated Ion Channels in Sperm: A Tale of Two Channels1Semantic proximity Read ↗

Intracellular events and signaling pathways involved in sperm acquisition of fertilizing capacity and acrosome reactionSemantic proximity Read ↗

Acrosome reaction: relevance of zona pellucida glycoproteinsSemantic proximity Read ↗

Lipid Modulation of Calcium Flux through CaV2.3 Regulates Acrosome Exocytosis and FertilizationSemantic proximity Read ↗

Research Progress on the Microregulatory Mechanisms of Fertilization: A ReviewSemantic proximity Read ↗

Molecular and Cellular Mechanisms of Sperm-Oocyte Interactions Opinions Relative to in Vitro Fertilization (IVF)Semantic proximity Read ↗

Penetration, Adhesion, and Fusion in Mammalian Sperm-Egg InteractionSemantic proximity Read ↗

Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reactionSemantic proximity Read ↗

Cell Adhesion and Fertilization: Steps in Oocyte Transport, Sperm-Zona Pellucida Interactions, and Sperm-Egg Fusion1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.