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Article

Integration of expression quantitative trait loci and pleiotropy identifies a novel psoriasis susceptibility gene, PTPN1.

The journal of gene medicine - 1 Jan 2017

Yin Xianyong, Lin Yuan, Shen Changbing, Wang Ling, Zuo Xianbo, Zheng Xiaodong, Yang Sen, Liu Jianjun, Wilhelmsen Kirk C, Zhang Xuejun

Abstract excerpt

BACKGROUND: Psoriasis is a common inflammatory skin disease, whereas schizophrenia is a psychiatric disorder with substantial comorbidity. Although these two disorders manifest with apparently unrelated phenotypes, there is some evidence suggesting that they share common genetic factors. METHODS: We implemented a genetic analysis incorporating pleiotropy and annotation to genome-wide association summary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27976820
DOI: 10.1002/jgm.2939

Genes

PTPN1
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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