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Article

Genomic correlation, shared loci, and causal relationship between insomnia and psoriasis: a large-scale genome-wide cross-trait analysis.

Archives of dermatological research - 21 Jun 2024

Wang Qing, Wu Yuan, Wang Xuehua, Zhang Junhong, Li Li, Wu Jingjing, Lu Yue, Han Ling

Abstract excerpt

Psoriasis and insomnia have co-morbidities, however, their common genetic basis is still unclear. We analyzed psoriasis and insomnia with summary statistics from genome-wide association studies. We first quantified overall genetic correlations, then ascertained multiple effector loci and expression-trait associations, and lastly, we analyzed the causal effects between psoriasis and insomnia. A prevalent genetic...

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PMID: 38904754
DOI: 10.1007/s00403-024-03178-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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