Article
A Genome-Wide SNP Linkage Analysis Suggests a Susceptibility Locus on 6p21 for Ankylosing Spondylitis and Inflammatory Back Pain Trait.
PloS one - 1 Jan 2016
Zhang Yanli, Liao Zetao, Wei Qiujing, Pan Yunfeng, Wang Xinwei, Cao Shuangyan, Guo Zishi, Wu Yuqiong, Rong Ju, Jin Ou, Xu Manlong, Lin Zhiming, Gu Jieruo
Abstract excerpt
OBJECTIVES: To screen susceptibility loci for ankylosing spondylitis (AS) using an affected-only linkage analysis based on high-density single nucleotide polymorphisms (SNPs) in a genome-wide manner. PATIENTS AND METHODS: AS patients from ten families with Cantonese origin of China were enrolled in the study. Blood samples were genotyped using genomic DNA derived from peripheral blood leukocytes by Illumina...
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