Differentiation of hepatitis B virus genotypes D and E by ELISA using monoclonal antibodies to epitopes on the preS2-region product.

doi:10.1016/s0166-0934(00)00153-1

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Article

Differentiation of hepatitis B virus genotypes D and E by ELISA using monoclonal antibodies to epitopes on the preS2-region product.

Journal of virological methods - 1 Jun 2000

Usuda S, Okamoto H, Tanaka T, Kidd-Ljunggren K, Holland P V, Miyakawa Y, Mayumi M

Abstract excerpt

An enzyme-linked immunosorbent assay (ELISA) has been described for serological determination of hepatitis B virus genotypes, using monoclonal antibodies (mAb) against seven distinct epitopes (b, m, k, s, u, f and g) on the preS2-region products of hepatitis B surface antigen (HBsAg). The usefulness of this method for serological detection of genotype E, however, was theoretical, because no HBsAg samples of this...

Topics

Africa
Amino Acid Sequence
Antibodies, Monoclonal
Antibody Specificity
China
DNA, Viral
Enzyme-Linked Immunosorbent Assay
Epitopes
Genotype
Hepatitis B
Hepatitis B Antibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B Surface Antigens

Hepatitis B virus

Humans

India

Molecular Sequence Data

Sequence Alignment

United States

Source

Open in PubMed

Identifiers

PMID: 10856755
DOI: 10.1016/s0166-0934(00)00153-1

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