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Article

Pharmacogenetics of Clinical Response to Risperione

1 Jan 2013

Abstract excerpt

Despite risperidone's proven safety and efficacy, existing pharmacogenetic knowledge could be applied to improve its clinical use. The present work aims to summarize the information about genetic polymorphisms affecting risperidone adverse reactions and efficacy during routine clinical practice. The most relevant genes involved in the metabolism of the drug (i.e., CYP2D6, CYP3A and ABCB1) appear to have the...

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PMID: 23327578
DOI: 10.2217/pgs.12.201

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