Article
Influence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6*10/*10.
British journal of pharmacology - 1 Sept 2011
Yoo Hee-Doo, Lee Sang-No, Kang Hyun-Ah, Cho Hea-Young, Lee Il-Kwon, Lee Yong-Bok
Abstract excerpt
BACKGROUND AND PURPOSE: The objective of this study was to investigate the combined influence of genetic polymorphisms in ABCB1 and CYP2D6 genes on risperidone pharmacokinetics. EXPERIMENTAL APPROACH: Seventy-two healthy Korean volunteers receiving a single oral dose of 2 mg risperidone were incl...
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