Article
Genetic polymorphisms of UTS2 rs2890565 Ser89Asn in cardiac hypertrophy in Chinese Han population.
Postgraduate medical journal - 1 Jul 2017
Zhao Jing, Jiang Jie, Wang Jie, Liu Lin, Han Xiao-Ning, Chu Song-Yun, Xue Lin, Ding Wen-Hui
Abstract excerpt
OBJECTIVE: Cardiac hypertrophy is the heart's response to a variety of extrinsic and intrinsic stimuli, some of which might finally lead up to a maladaptive state. Clinical evidence, in vitro and in vivo studies have implicated urotensin II (U-II/UTS2) in the development of cardiac hypertrophy, contributing to the (patho)-physiological regulation of cardiovascular homeostasis in humans. Several genes are...
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