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Article

The role of a common TNNT2 polymorphism in cardiac hypertrophy.

Journal of human genetics - 1 Jan 2004

Komamura Kazuo, Iwai Naoharu, Kokame Koichi, Yasumura Yoshio, Kim Jiyoong, Yamagishi Masakazu, Morisaki Takayuki, Kimura Akinori, Tomoike Hitonobu, Kitakaze Masafumi, Miyatake Kunio

Abstract excerpt

We found a five-basepair insertion/deletion polymorphism in intron 3 of TNNT2, one of the genes responsible for hypertrophic cardiomyopathy. These five bases may be part of an intronic polypyrimidine tract sequence that may affect splicing. The purpose of the study was to examine the association of the polymorphism with cardiac hypertrophy. The study population consisted of 151 subjects with prominent concentric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14986170
DOI: 10.1007/s10038-003-0121-4

Genes

TNNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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