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Article

Association analysis of urotensin II gene (UTS2) and flanking regions with biochemical parameters related to insulin resistance.

PloS one - 29 Apr 2011

Sáez María E, Smani Tarik, Ramírez-Lorca Reposo, Díaz Ignacio, Serrano-Ríos Manuel, Ruiz Agustín, Ordoñez Antonio

Abstract excerpt

BACKGROUND: Urotensin II (UII) is a potent vasoconstrictor peptide, which signals through a G-protein coupled receptor (GPCR) known as GPR14 or urotensin receptor (UTR). UII exerts a broad spectrum of actions in several systems such as vascular cell, heart muscle or pancreas, where it inhibits insulin release. OBJECTIVE: Given the reported role of UII in insulin secretion, we have performed a genetic association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21559414
DOI: 10.1371/journal.pone.0019327
PMCID: PMC3084835

Genes

UTS2
PER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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