Article
Analysis of HIV Diversity in HIV-Infected Black Men Who Have Sex with Men (HPTN 061).
PloS one - 1 Jan 2016
Chen Iris, Chau Gordon, Wang Jing, Clarke William, Marzinke Mark A, Cummings Vanessa, Breaud Autumn, Laeyendecker Oliver, Fields Sheldon D, Griffith Sam, Scott Hyman M, Shoptaw Steven, Del Rio Carlos, Magnus Manya, Mannheimer Sharon, Tieu Hong-Van, Wheeler Darrell P, Mayer Kenneth H, Koblin Beryl A, Eshleman Susan H
Abstract excerpt
BACKGROUND: HIV populations often diversify in response to selective pressures, such as the immune response and antiretroviral drug use. We analyzed HIV diversity in Black men who have sex with men who were enrolled in the HIV Prevention Trials Network 061 study. METHODS: A high resolution melting (HRM) diversity assay was used to measure diversity in six regions of the HIV genome: two in gag, one in pol, and...
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