Article
Genetic diversity of HIV in seminal plasma remains higher than in blood after short-term antiretroviral therapy.
Sexually transmitted infections - 1 Aug 2020
López Zúñiga Miguel Ángel, Chueca Natalia, de Salazar Adolfo, Fernández Caballero José Angel, Gutierrez Valencia Alicia, Vinuesa García David, Omar Mohamed Balgahata Mohamed, Hidalgo Tenorio Carmen, Lopez-Ruz Miguel Angel, Garcia Federico
Abstract excerpt
OBJECTIVE: To provide insight on viral kinetics and genetic diversity of HIV in seminal plasma at baseline and 1 month after initiating antiretroviral therapy (ART). PATIENTS AND METHODS: Blood and seminal samples from patients with newly diagnosed HIV were obtained before ART initiation (T0) and 1 month after ART initiation (T1). HIV env genetic diversity was studied using deep sequencing Nextera and V3...
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