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Article

The emerging role of epigenetic mechanisms in the etiology of neural tube defects.

Epigenetics - 1 Jul 2011

Greene Nicholas D E, Stanier Philip, Moore Gudrun E

Abstract excerpt

The molecular requirements for neural tube closure are complex. This is illustrated by the occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a variety of genes, pathways and cellular functions. NTDs are also prevalent birth defects in humans, affecting around 1 per 1000 pregnancies worldwide. In humans the causation is thought to involve the interplay of fetal genes and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21613818
DOI: 10.4161/epi.6.7.16400
PMCID: PMC3154428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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