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Article

The search for genetic determinants of human neural tube defects.

Current opinion in pediatrics - 1 Dec 2019

Wolujewicz Paul, Ross M Elizabeth

Abstract excerpt

PURPOSE OF REVIEW: An update is presented regarding neural tube defects (NTDs) including spina bifida and anencephaly, which are among the most common serious birth defects world-wide. Decades of research suggest that no single factor is responsible for neurulation failure, but rather NTDs arise from a complex interplay of disrupted gene regulatory networks, environmental influences and epigenetic regulation. A...

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Source

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Identifiers

PMID: 31693581
DOI: 10.1097/MOP.0000000000000817
PMCID: PMC6993899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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