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Article

Translational Safety Genetics.

Toxicologic pathology - 1 Jan 2017

Bhoumik Priyasma, Del Rio-Espinola Alberto, Hahne Florian, Moggs Jonathan, Grenet Olivier

Abstract excerpt

The emerging field of translational safety genetics is providing new opportunities to enhance drug discovery and development. Genetic variation in therapeutic drug targets, off-target interactors and relevant drug metabolism/disposition pathways can contribute to diverse drug pharmacologic and toxicologic responses between different animal species, strains and geographic origins. Recent advances in the sequencing...

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PMID: 27932582
DOI: 10.1177/0192623316675064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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