Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemical genetics: where genetics and pharmacology meet.

Cell - 9 Feb 2007

Knight Zachary A, Shokat Kevan M

Abstract excerpt

Genetics and pharmacology can elicit surprisingly different phenotypes despite targeting the same protein. This Essay explores these unexpected differences and their implications for biology and medicine.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allosteric Regulation
Share to Enzyme Inhibitors
Share to Genetic Techniques
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Phosphotransferases

Share to Proteins

Source

Identifiers

PMID: 17289560
DOI: 10.1016/j.cell.2007.01.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemical genetics: where genetics and pharmacology meet.PMID 17289560Read ↗

Frontiers in chemical genetics.Semantic proximity Read ↗

Chemical genetics: elucidating biological systems with small-molecule compounds.Semantic proximity Read ↗

Advances in chemical genetics.Semantic proximity Read ↗

Chemical genetic screening approaches to neurobiology.Semantic proximity Read ↗

Chemical genetics: an evolving toolbox for target identification and lead optimization.Semantic proximity Read ↗

Tuning up the right signal: chemical and genetic approaches to study GPCR functionsSemantic proximity Read ↗

Allele-specific chemical genetics: concept, strategies, and applications.Semantic proximity Read ↗

Genetics. Delivering new disease genes.Semantic proximity Read ↗

The emerging power of chemical genetics.Semantic proximity Read ↗

Genetics in drug discovery and development: challenge and promise of individualizing treatment in common complex diseases.Semantic proximity Read ↗

Therapeutic promise of molecular genetics.Semantic proximity Read ↗

Chemical genetics-based target identification in drug discovery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.