Article
The pharmacogenomics of P-glycoprotein and its role in veterinary medicine.
Journal of veterinary pharmacology and therapeutics - 1 Aug 2008
Martinez M, Modric S, Sharkey M, Troutman L, Walker L, Mealey K
Abstract excerpt
Despite advancements in pharmacogenetics in human medicine, the incorporation of pharmacogenetics into veterinary medicine is still in its early stages of development. To date, efforts to understand the pharmacologic impact of genetic variation in veterinary species have largely focused on genes encoding for the membrane transporter, P-glycoprotein (P-gp). The emphasis on the role of P-gp is largely because of...
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